职    称

助理研究员

出生年月

1988.1

导师类别

硕 导

导师学位

博士

联系电话

E-mail

lengling@tjutcm.edu.cn

招生要求

无

研究方向

细胞外囊泡在心血管疾病治疗中的作用研究

简    介

冷玲，助理研究员，博士、博士后。致力于研究外泌体、植物外囊泡等生物纳米囊泡的分离、鉴定及其在疾病治疗中的作用，熟练掌握中药心血管药理研究相关技术和方法，主持国家自然科学基金青年基金和天津市教育委员会科研计划项目各1项，参与国家重点研发计划1项，主持和参与横向课题5项。以第一作者（含共同第一作者）在 Molecular therapy、Phytotherapy research、Journal of Ethnopharmacology等国际优秀期刊上发表SCI文章8篇。担任天津市中医药学会分会委员心血管病专业委员会青年编委，担任《针灸与草药（英文）》期刊青年编委。荣获中医药研究院“担当奉献”先进个人，入选中医药研究院第二届“青年拔尖人才托举计划”。

代表性论文：

1.            Leng L^#, Dong X^#,   Gao X, Ran N, Geng   M, Zuo B, Wu Y, Li W, Yan H, Han G^*, Yin   H^*. Exosome-mediated   improvement in membrane integrity and muscle   function in dystrophic mice. Mol   Ther. 2021, 29(4):1459-1470.

2.            Leng L^#, Li J^#,   Luo XM, Kim JY, Li YM,   Guo XM, Chen X, Yang QY, Li G^*, Tang   NJ^*. Polychlorinated   biphenyls and breast cancer: A   congener-specific meta-analysis. Environ Int.   2016, 88:133-141.

3.            Leng L, Chen X, Li   CP, Luo XY, Tang NJ. 2,3,7,8-Tetrachlorodibezo-p-dioxin   exposure and   prostate cancer: a meta-analysis of cohort studies. Public   Health.   2014, 128(3):207-13.

4.            Shan A^#,   Leng     L^#, Li J, Luo XM, Fan YJ, Yang Q, Xie QH, Chen   YS, Ni CS, Guo   LM, Tang H, Chen X^*, Tang NJq^*.   TCDD-induced antagonism   of MEHP-mediated migration and invasion partly   involves aryl hydrocarbon   receptor in MCF7 breast cancer cells. J   Hazard Mater. 2020, 398:122869.

5.            Wei J^#,   Leng     L^#, Sui Y, Song S, Owusu FB, Li X, Cao Y, Li P,   Wang H, Li R,   Yang W, Gao X^*, Wang Q^*. Phenolic   acids from Prunella   vulgaris alleviate cardiac remodeling following   myocardial infarction   partially by suppressing NLRP3 activation.   Phytother Res. 2023.

6.            Tong W^#,   Leng     L^#, Wang Y, Guo J, Owusu FB, Zhang Y, Wang F, Li   R, Li Y,   Chang Y, Wang Y^*, Wang Q^*. Buyang   huanwu decoction   inhibits diabetes-accelerated atherosclerosis via   reduction of   AMPK-Drp1-mitochondrial fission axis. J Ethnopharmacol.   2023, 312: 116432.

7.    Tao PY^#, Leng L^#,   Liu   K, Zhou RH, Hu YC, Wu SJ, Xiao YD^*, Liu J^*.     Determination of risk factors for predicting the onset of symptoms in     asymptomatic COVID-19 infected patients. Int J Med Sci. 2020,   17(14):2187-2193.   doi: 10.7150/ijms.47576.

8.   Li Y, Guo R, Oduro PK, Sun T, Chen H, Yi     Y, Zeng W, Wang Q, Leng L^*, Yang L^*,   Zhang J^*.   The Relationship Between Porphyromonas Gingivalis   and Rheumatoid Arthritis: A   Meta-Analysis. Front Cell Infect   Microbiol. 2022, 12:956417.